36926-41-7 Usage
Uses
Used in Organic Synthesis:
2,4-dichloro-6-phenylthieno[3,2-d]pyrimidine is used as a building block in organic synthesis for the development of new compounds with potential applications in various industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,4-dichloro-6-phenylthieno[3,2-d]pyrimidine is used as a key intermediate in the synthesis of new drugs. Its unique structure allows for the exploration of its potential therapeutic effects in the treatment of various diseases.
Used in Agrochemical Development:
2,4-dichloro-6-phenylthieno[3,2-d]pyrimidine is also utilized in the agrochemical sector as a precursor for the development of new pesticides. Its chemical properties make it a promising candidate for the creation of effective and targeted pest control solutions.
Safety Considerations:
It is important to handle 2,4-dichloro-6-phenylthieno[3,2-d]pyrimidine with care, as it may pose health and environmental risks if not managed properly. Proper safety measures should be taken during its synthesis, storage, and use to minimize potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 36926-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,9,2 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 36926-41:
(7*3)+(6*6)+(5*9)+(4*2)+(3*6)+(2*4)+(1*1)=137
137 % 10 = 7
So 36926-41-7 is a valid CAS Registry Number.
36926-41-7Relevant academic research and scientific papers
Discovery and SAR of a novel series of Natriuretic Peptide Receptor-A (NPR-A) agonists
Iwaki, Takehiko,Nakamura, Yuji,Tanaka, Taisaku,Ogawa, Yasuyuki,Iwamoto, Osamu,Okamura, Yoshihiko,Kawase, Yumi,Furuya, Mayumi,Oyama, Yoshiaki,Nagayama, Takahiro
supporting information, p. 4904 - 4907 (2017/09/29)
Novel thienopyrimidine compounds 2 and 3 were discovered from high-throughput screening as Natriuretic Peptide Receptor A (NPR-A) agonists. Scaffold hopping of a thienopyrimidine ring to a quinazoline ring, introduction of the basic functional group and optimization of the substituent on the 6-position of the benzene ring of quinazoline led to improved agonistic activity. We discovered compound 48, which showed potent agonistic activity for NPR-A with an EC50 value of 0.073 μM, indicating 350-fold potency compared to the hit compound 3.
