369360-84-9

Upstream product

• 25413-70-1 N-nitroso-N-pentyl-aniline 

Downstream Products

• 6299-90-7 3-phenylbenzo-1,2,4-triazine 
• 369357-01-7 (2RS,3R)-3-amino-4-cyclohexyl-2-hydroxy-N'-pentyl-N'-phenylbutanohydrazide 

Relevant academic research and scientific papers

Cobalt-Catalyzed, Directed Intermolecular C-H Bond Functionalization for Multiheteroatom Heterocycle Synthesis: The Case of Benzotriazine

Transition-metal-catalyzed, directed intermolecular C-H bond functionalization is synthetically useful but heavily underexplored in multiheteroatom heterocycle synthesis. Herein we report a cobalt catalytic method for the formation of a three-nitrogen-bearing benzotriazine scaffold via the coupling of arylhydrazine and oxadiazolone. This synthetic protocol features a low-cost base metal catalyst, a maximum number of heteroatoms built into a heterocycle, a distinct synthetic logic for benzotriazines, a superior step economy, and a broad substrate scope.