369363-62-2

Basic information

• Product Name: 1H-1,2,3-Triazole, 4-[4-(trifluoromethyl)phenyl]-
• CAS NO: 369363-62-2
• Molecular Formula: C9H6F3N3
• Molecular Weight: 213.162
• Mol File: 369363-62-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1H-1,2,3-Triazole, 4-[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,3-Triazole, 4-[4-(trifluoromethyl)phenyl]-(369363-62-2)
• EPA Substance Registry System: 1H-1,2,3-Triazole, 4-[4-(trifluoromethyl)phenyl]-(369363-62-2)

Safety Data

• Hazardous Substances Data: 369363-62-2(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 75-52-5 nitromethane 
• 152782-75-7 sodium hydroxy(4-(trifluoromethyl)phenyl)methanesulfonate 
• 705-31-7 4-trifluoromethylphenylacetylene 
• 131356-53-1 1-(2,2-dibromovinyl)-4-(trifluoromethyl)benzeney 
• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 99696-01-2 p-trifluoromethyl-trans-β-nitrostyrene 
• 93628-97-8 1-(2-nitrovinyl)-4-trifluoromethylbenzene 

Relevant articles and documents

Dipolar HCP materials as alternatives to DMF solvent for azide-based synthesis

Hypercrosslinked polymers HCP-DMF and HCP-DMF-SO3H containing abundant and flexible DMF moieties were designed and synthesized. Benefitting from the solvation microenvironment provided by the pseudo-DMF moities, the polar HCPs manifested outstanding performances in the conversions of NaN3 to benzylic azides and 1,2,3-triazoles in EtOH (95%), respectively, avoiding the use of risky DMF and improving the separation processes of the products.

Facile Synthesis of 1,3,5-Triarylbenzenes and 4-Aryl-NH-1,2,3-Triazoles Using Mesoporous Pd-MCM-41 as Reusable Catalyst

We report mesoporous nano-Pd-MCM-41 catalyzed rapid and efficient synthesis of 1,3,5-triarylbenzenes via de-nitrative cyclotrimerization of β-nitrostyrenes. All the reactions were very fast and high yielding. The Pd-MCM-41 was also very effective in catalyzing de-nitrative [3+2] cycloaddition of β-nitrostyrenes with TMSN3 to synthesize 4-aryl-NH-1,2,3-triazoles. The catalyst was reused at least up to eight times with minimum loss of catalytic activity.

Copper(I)-Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Azidoformates and Aryl Terminal Alkynes

The copper(I)-catalyzed azide-alkyne cycloaddition reaction has been extensively studied and widely applied in organic synthesis. However, the formation of 1,2,3-triazoles with electron-deficient azide has been a challenging problem. In this report, we ha