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ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 369397-75-1 Structure
  • Basic information

    1. Product Name: ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate
    2. Synonyms: ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate
    3. CAS NO:369397-75-1
    4. Molecular Formula: C12H14N2O3S
    5. Molecular Weight: 266.31616
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 369397-75-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate(369397-75-1)
    11. EPA Substance Registry System: ethyl (5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetate(369397-75-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 369397-75-1(Hazardous Substances Data)

369397-75-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 369397-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,9,3,9 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 369397-75:
(8*3)+(7*6)+(6*9)+(5*3)+(4*9)+(3*7)+(2*7)+(1*5)=211
211 % 10 = 1
So 369397-75-1 is a valid CAS Registry Number.

369397-75-1Downstream Products

369397-75-1Relevant articles and documents

Antiproliferative activity of novel thiophene and thienopyrimidine derivatives

Ghorab,Al-Dhfyan,Al-Dosari,El-Gazzar,Alsaid

, p. 313 - 320 (2014)

A novel series of newly synthesized thiophene derivatives, ethyl-4,5-dimethyl-2-(3-(3,4,5-trimethoxyphenyl)thioureido)thiophene-3- carboxylate 3, ethyl-2-[(2-(dimethylamino)ethoxy)mercapto)methyleneamino)]-4,5- dimethyl-thiophene-3-carboxylate 9, thienopyrimidines 4, 7, 10-20, triazolothienopyrimidines 5, 6 were prepared and tested for their antiproliferative activity. The structures of the synthesized compounds were confirmed on the basis of elemental analysis, IR, 1H-NMR, 13C-NMR and mass spectral data. The results showed that the synthesized compounds were more active on breast cancer than on colon cancer cell lines and the most potent compounds in this study are compounds 3 and 13 which exerted remarkable activity against MDA-MB-231 (breast cancer) and HT-29 (colon cancer) cell lines with IC50 values (40.68, 49.22 μM) for compound 3 and (34.04, 45.62 μM) for compound 13. Also, compounds 4-6, 9 showed a moderate activity against breast cancer cell line, while compounds 15, 19 and 20 showed no activity. Georg Thieme Verlag KG Stuttgart New York.

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