369403-44-1

Basic information

• Product Name: 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid
• Synonyms: 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid;a-(Boc-aMino)-biphenyl-4-acetic acid
• CAS NO: 369403-44-1
• Molecular Formula: C₁₉H₂₁NO₄
• Molecular Weight: 327.37434
• Mol File: 369403-44-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid(369403-44-1)
• EPA Substance Registry System: 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid(369403-44-1)

Safety Data

• Hazardous Substances Data: 369403-44-1(Hazardous Substances Data)

Usage

General Description

2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid is a chemical compound that belongs to the class of amino acids. It is commonly used in the chemical synthesis of peptides and pharmaceutical drugs. The compound consists of a biphenyl group and a Boc-protected amino group, making it suitable for coupling reactions in peptide synthesis. It is also used as a building block in the production of diverse pharmaceutical compounds due to its stability and compatibility in chemical reactions. Additionally, it has potential applications in the development of new drug molecules and materials with specific properties. Overall, 2-(4-Biphenylyl)-2-(Boc-aMino)acetic Acid plays a crucial role in organic and medicinal chemistry, serving as a key intermediate in the synthesis of biologically active compounds.

Upstream product

• 917925-71-4 2-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)acetic acid 
• 98-80-6 phenylboronic acid 
• 42718-15-0 methyl 2-amino-2-(4-bromophenyl)acetate 
• 709665-73-6 methyl 2-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)acetate 
• 119397-06-7 2-amino-2-(4-bromophenyl)acetic acid 

Downstream Products

• 221101-61-7 2-([1,1’-biphenyl]-4-yl)glycine 

Relevant articles and documents

Synthesis method of 2-([1, 1 '-biphenyl]-4-yl)-2-glycine compound

The invention relates to a synthesis method of a 2-([1, 1 '-biphenyl]-4-yl)-2-glycine compound. The method comprises the following steps: performing suzuki reaction on a compound as shown in a formulaI and a compound as shown in a formula II in the presence of alkali, a solvent and a catalyst under inert gas protection and microwave-assisted conditions to prepare an intermediate compound, and then deprotecting the intermediate compound to prepare a compound as shown in a formula III, wherein the structural formula of the compound shown in the formula I is shown in the specification, the structural formula of the compound shown in the formula II is shown in the specification, the structural formula of the compound shown in the formula III is shown in the specification, and in the formula Iand the formula III, R is one of H, alkyl, alkoxy, halogen and trifluoromethyl. The synthesis method is low in toxicity, high in safety coefficient, easy and convenient to operate, easy to control and efficient in reaction, and the yield reaches up to 81% or above. In the synthesis method, microwave assistance is added for a certain time in the suzuki reaction process, so that the reaction is promoted, the reaction efficiency is effectively improved, and the reaction time is shortened.