36944-72-6Relevant academic research and scientific papers
Rh(III)-Catalyzed Oxidative Annulation Leading to Substituted Indolizines by Cleavage of C(sp2)-H/C(sp3)-H Bonds
Shen, Bingxue,Li, Bin,Wang, Baiquan
, p. 2816 - 2819 (2016)
Rhodium(III)-catalyzed oxidative annulation reactions of pyridinium trifluoromethanesulfonate salts with alkynes leading to substituted indolizines by cleavage of C(sp2)-H/C(sp3)-H bonds are developed. The starting materials are readily available, and the reactions have a broad substrate scope. This reaction overcomes some drawbacks of the previous indolizine synthetic methods and provides a new efficient route to indolizine derivatives.
