N-(O-phosphono-L-seryl)-L-glutamic acid, also known as phosphonomethylserine or PMS, is a synthetic amino acid analog that plays a crucial role in various biological processes. It is structurally similar to the naturally occurring amino acid serine, with a phosphonate group replacing the hydroxyl group. This modification makes PMS a potent inhibitor of several enzymes, particularly those involved in the biosynthesis of the cell wall in bacteria. The phosphonate group mimics the transition state of the enzyme's reaction, thereby blocking the enzyme's active site and halting the synthesis of peptidoglycan, a key component of bacterial cell walls. This leads to the disruption of bacterial cell division and ultimately causes cell death. PMS is also known for its potential applications in the development of new antibiotics, particularly against antibiotic-resistant bacteria, and in the study of enzyme mechanisms and metabolic pathways.
3695-66-7
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Basic information
- Product Name: N-(O-phosphono-L-seryl)-L-glutamic acid
- Synonyms: N-(O-phosphono-L-seryl)-L-glutamic acid
- CAS NO:3695-66-7
- Molecular Formula:
- Molecular Weight: 314.189
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-(O-phosphono-L-seryl)-L-glutamic acid(CAS DataBase Reference)
- NIST Chemistry Reference: N-(O-phosphono-L-seryl)-L-glutamic acid(3695-66-7)
- EPA Substance Registry System: N-(O-phosphono-L-seryl)-L-glutamic acid(3695-66-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3695-66-7(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3695-66-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,9 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.Calculate Digit Verification of CAS Registry Number 3695-66:
(6*3)+(5*6)+(4*9)+(3*5)+(2*6)+(1*6)=117
117 % 10 = 7
So 3695-66-7 is a valid CAS Registry Number.
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N-(O-phosphono-L-seryl)-L-glutamic acid
