36960-37-9Relevant academic research and scientific papers
A highly stereoselective synthesis of E-(but-1-en-3-yne-1-sulfonyl) hetarenes and disubstituted 2-benzothiazolyl alkynes by palladium catalyzed sonogashira type coupling of 2-chlorovinylsulfones
Visnevska, Julija,Belyakov, Sergey,Abele, Edgars
experimental part, p. 250 - 256 (2012/07/17)
Abstract: Novel and highly stereoselective route to E-(but-1-en-3-yne-1- sulfonyl)hetarenes by palladium catalyzed Sonogashira type coupling of unstable E-2-chlorovinylsulfonylbenzene and E-2-(2-chlorovinylsulfonyl)pyridine was presented. Usage of potassium phosphate as novel base in Sonogashira reaction was demonstrated. Unusual coupling products in the Sonogashira reaction of E-2-(2-chlorovinylsulfanyl)benzothiazole with different alkynes were obtained.
A stereoselective cis-enyne synthesis using vinyl sulfone chemistry
Holmes, Andrew B.,Pooley, Guy R.
, p. 7775 - 7792 (2007/10/02)
The trans-sulfonyl enyne 8 was deprotonated using lithium diisopropylamide to provide a cis-enyne onion which was coupled with a variety of carbonyl compounds to provide, in high yields, a range of silyl-protected phenylsulfonyl enynes. These were desulfo
