369657-20-5

Upstream product

• 496067-57-3 (S)-2-[(Adamantane-1-carbonyl)-amino]-succinic acid dimethyl ester 
• 2094-72-6 1-Adamantanecarbonyl chloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 496067-58-4 Adamantane-1-carboxylic acid ((S)-3-hydroxy-1-hydroxymethyl-propyl)-amide 

Downstream Products

• 496067-64-2 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-(3,5-ditert-butyl-4-methoxyl-phenyl)imidazolium iodide 
• 496067-66-4 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-(2,5-ditert-butylphenyl)imidazolium iodide 
• 496067-61-9 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-diphenylmethylimidazolium iodide 
• 496067-63-1 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-(2,4,6-trimethylphenyl)imidazolium iodide 
• 496067-62-0 1-(((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-cyclohexylimidazolium iodide 
• 369657-24-9 1-((((S)-4',5'-dihydro-2'-(1-adamantyl)-4'-oxazolyl)ethyl)-3-(2,6)-diisopropylphenyl)imidazolium iodide 

Relevant academic research and scientific papers

Improved catalysts for the iridium-catalyzed asymmetric isomerization of primary allylic alcohols based on charton analysis

An improved generation of chiral cationic iridium catalysts for the asymmetric isomerization of primary allylic alcohols is disclosed. The design of these air-stable complexes relied on the preliminary mechanistic information available, and on Charton analyses using two preceding generations of iridium catalysts developed for this highly challenging transformation. Sterically unbiased chiral aldehydes that were not accessible previously have been obtained with high levels of enantioselectivity, thus validating the initial hypothesis regarding the selected ligand-design elements. A rationale for the high enantioselectivities achieved in most cases is also presented. Achieving enantioselectivity: An improved generation of chiral cationic iridium catalysts for the asymmetric isomerization of primary allylic alcohols is disclosed. The design of these air-stable complexes relies on preliminary mechanistic information and on Charton analyses using two preceding generations of iridium catalysts developed for this highly challenging transformation (see figure).

Optically active iridium imidazol-2-ylidene-oxazoline complexes: Preparation and use in asymmetric hydrogenation of arylalkenes

This work explores the potential of iridium complexes of the N-heterocyclic carbene oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes. The accessible carbene precursors, imidazolium salts 2, and robust iridium complexes 5 facilitated a disco