37003-80-8

Upstream product

• 18096-70-3 3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one 
• 62-53-3 aniline 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 142-04-1 aniline hydrochloride 

Downstream Products

• 1401856-06-1 ((4S,6R)-4-(4-chlorophenyl)-6-hydroxy-1-phenyl-1,4,5,6-tetrahydropyridin-3-yl)(4-methoxyphenyl)methanone 
• 1401855-92-2 ((4S,6R)-6-hydroxy-1,4-diphenyl-1,4,5,6-tetrahydropyridin-3-yl)(4-methoxyphenyl)methanone 
• 1418126-86-9 methyl 5-(4-methoxybenzoyl)-2-oxo-1-phenyl-1,2-dihydropyridine-4-carboxylate 

Relevant academic research and scientific papers

Enantioselective organocatalytic domino synthesis of tetrahydropyridin-2- ols

The asymmetric synthesis of tetrahydropyridin-2-ols from enals and enaminones is described. The organocatalytic domino reaction involves a Michael addition-hemiaminalization sequence using the Jorgensen-Hayashi catalyst. Dehydration or oxidation leads to the corresponding 1,4-dihydro-pyridines or 3,4-dihydropyridin-2-ones in a one-pot fashion. The Royal Society of Chemistry 2012.

Efficient palladium-catalyzed Suzuki cross-coupling reaction with β-ketoamine ligands

A series of β-ketoamine ligands with different steric and electronic substituents on the backbone and with aniline moieties have been synthesized and characterized. In the presence of PdCl2, catalytic studies indicated that they are effective l