370069-26-4

Basic information

• Product Name: {2-[(1-tert-butylcarbamoyl-3-methyl-butyl)-(2-fluoro-5-nitro-benzoyl)-amino]-phenyl}-carbamic acid tert-butyl ester
• CAS NO: 370069-26-4
• Molecular Weight: 544.623
• Mol File: 370069-26-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: {2-[(1-tert-butylcarbamoyl-3-methyl-butyl)-(2-fluoro-5-nitro-benzoyl)-amino]-phenyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {2-[(1-tert-butylcarbamoyl-3-methyl-butyl)-(2-fluoro-5-nitro-benzoyl)-amino]-phenyl}-carbamic acid tert-butyl ester(370069-26-4)
• EPA Substance Registry System: {2-[(1-tert-butylcarbamoyl-3-methyl-butyl)-(2-fluoro-5-nitro-benzoyl)-amino]-phenyl}-carbamic acid tert-butyl ester(370069-26-4)

Safety Data

• Hazardous Substances Data: 370069-26-4(Hazardous Substances Data)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 7304-32-7 2-fluoro-5-nitrobenzoic acid 
• 146651-75-4 tert–butyl (2–aminophenyl)carbamate 
• 590-86-3 isovaleraldehyde 

Relevant articles and documents

Two-step solution-phase synthesis of novel benzimidazoles utilizing a UDC (Ugi/de-Boc/cyclize) strategy

The novel solution-phase synthesis of an array of biologically relevant benzimidazoles in a simple two-step procedure is revealed. Transformations are carried out in excellent yield by condensation of mono-Boc protected ortho-phenylene diamine and supporting Ugi reagents. Subsequent acid treatment and evaporation affords benzimidazoles in good to excellent yield. The described protocol represents a highly attractive solution-phase procedure for the rapid generation of benzimidazole libraries.