37010-62-1 Usage
Molecular Weight
252.69 g/mol
Chemical Structure
A pyrrolidine-2,5-dione derivative with a 4-chlorophenyl group attached to the nitrogen atom and a methylene group (-CH2-) between the nitrogen and the carbonyl group.
Development
Initially developed as a sedative and hypnotic agent.
Teratogenic Effects
Found to cause severe birth defects when taken during pregnancy.
Anti-Inflammatory Properties
Exhibits anti-inflammatory effects by inhibiting the production of tumor necrosis factor-alpha (TNF-alpha), a pro-inflammatory cytokine.
Immunomodulatory Properties
Modulates the immune system, which contributes to its use in treating certain conditions.
Anti-Angiogenic Properties
Inhibits the formation of new blood vessels, which can be beneficial in treating certain diseases.
Medical Uses
Used to treat conditions such as leprosy, multiple myeloma, and certain autoimmune disorders.
Controversial History
Its teratogenic effects led to severe birth defects and its withdrawal from the market as a sedative and hypnotic agent.
Current Importance
Despite its controversial history, thalidomide continues to be an important drug in certain medical treatments and research.
Check Digit Verification of cas no
The CAS Registry Mumber 37010-62-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,1 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 37010-62:
(7*3)+(6*7)+(5*0)+(4*1)+(3*0)+(2*6)+(1*2)=81
81 % 10 = 1
So 37010-62-1 is a valid CAS Registry Number.
37010-62-1Relevant academic research and scientific papers
Modification of Poly(vinyl chloride) by N -Phenyl Itaconimides for the Improvement of Its Thermal Stability
Elsharif, Asma M.,Al-Ghamdi, Azza A.,Abdel-Naby, Abir S.
, (2019/08/08)
Poly(vinyl chloride) (PVC) is modified by N-phenyl itaconimide derivatives (N-(RPh)IM) as modifying agents or graft comonomers. The resulting modified polymers or graft copolymers were characterized using FTIR and UV/Vis spectrophotometry. The thermal pro
Synthesis of cyclic imides (methylphtalimides, carboxylic acid phtalimides and itaconimides) and evaluation of their antifungal potential
Stiz, Dorimar,Corrêa, Rogério,D'Auria, Felicia D.,Simonetti, Giovanna,Cechinel-Filho, Valdir
, p. 647 - 654 (2016/10/18)
Background: This paper describes the synthesis of three different subfamilies of cyclic imides: methylphtalimides, carboxyl acid phtalimides and itaconimides. Methods: Fifteen compounds (five of each sub-family) were obtained by the reaction of appropriat
1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same
-
, (2008/06/13)
Substituted 1-phenyl-3-methyl-pyrrolidinediones of the general formula: STR1 in which R may represent fluorine, chlorine, bromine, iodine, CN, SCN or methanesulfonyl, Z represents one or more of the same or different substituents selected from fluorine, c
