37032-45-4Relevant academic research and scientific papers
A BHT-regulated chemoselective access to monofluorinated chromones
Chen, Guang-Jian,Chen, Xiao-Qing,Hu, Yuan-Zhuo,Xia, Peng-Jiu,Xiang, Hao-Yue,Xie, Zhen-Zhen,Yang, Hua,Zhao, Qing-Lan,Zheng, Lan
, (2020)
A BHT-regulated chemoselective monofluorination of enaminones with Selectfluor under mild reaction conditions was unveiled for the first time. As a result, an array of monofluorinated chromones were efficiently assembled in a simple operational manner. Moreover, the scalability of this protocol and the versatility for the downstream transformations of the obtained fluorinated chromones to installing diverse nitrogen-containing heterocycles greatly broaden the practical applications of this developed protocol.
