37047-16-8Relevant academic research and scientific papers
IODINE-INDUCED IMINOTHIOLACTONIZATION OF γ,δ-UNSATURATED SECONDARY THIOAMIDES, NEW ENTRY TO 2-ACETOAMIDOTHIOPHENES
Takahata, Hiroki,Suzuki, Toshiaki,Maruyama, Mihoko,Moriyama, Keiko,Mozumi, Mayumi,et.al.
, p. 4777 - 4786 (2007/10/02)
Iodine-induced cyclization of γ,δ-unsaturated secondary thioamides 1 proceeded regio- (5-exo-trigonal) and chemo- (sulfur-carbon bond formation)selectively, providing iminothiolactones 2, which were converted in two-step sequences (dehydroiodination and N-acetylation) into 2-acetoamidothiophenes 4.This procedure was performed in one flask to afford polysubstituted 2-aminothiophenes.
THIO-CLAISEN REARRANGEMENT OF CYCLIC S-ALLYLTHIOIMIDATES
Takahata, Hiroki,Banba, Yasunori,Mozumi, Mayumi,Yamazaki, Takao
, p. 947 - 950 (2007/10/02)
Palladium(II)-catalyzed or non-catalyzed thio-Claisen rearrangement of cyclic S-allylthioimidates is described.
