370586-05-3 Usage
Uses
Used in Pharmaceutical Industry:
CID 797718 is used as a PKD1 inhibitor for its potential role in the development of therapeutic agents targeting various diseases. Its ability to inhibit PKD1, CAK, and PLK1 makes it a promising candidate for research and development in the pharmaceutical industry.
Used in Cancer Research:
CID 797718 is used as a research tool in cancer biology to study the role of PKD1, CAK, and PLK1 in tumor growth and progression. By inhibiting these kinases, it can provide insights into the molecular mechanisms underlying cancer development and help in the identification of potential therapeutic targets.
Used in Drug Synthesis:
CID 797718 is used as a byproduct in the synthesis of CID755673, which may have implications for the development of new drugs or drug candidates with similar or improved properties. This can contribute to the advancement of drug discovery and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 370586-05-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,0,5,8 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 370586-05:
(8*3)+(7*7)+(6*0)+(5*5)+(4*8)+(3*6)+(2*0)+(1*5)=153
153 % 10 = 3
So 370586-05-3 is a valid CAS Registry Number.
370586-05-3Relevant academic research and scientific papers
Lyubchanskaya,Alekseeva,Savina,Shashkov,Granik
, p. 1886 - 1893 (2002)
α-Oxolactam enamines, namely, 3-piperidino-5,6-dihydropyridin-2(1H)-one (1a) and 3-piperidino-1,5,6,7-tetrahydroazepin-2-one (1b), were introduced for the first time into the Nenitzescu reaction. The processes yield cyclic adducts 3a-e, 6. On heating in acetic acid, they are transformed into benzofuropyridone 7 and benzofuroazepinones 10a,d, and 12 and, unexpectedly, into chromenopyrrole 8 and chromenopyridines 9a-d and 11.
Novel synthesis of chromene and benzofuran derivatives via the Nenitzescu reaction
Lyubchanskaya, Valeria M.,Alekseeva, Lyudmila M.,Savina, Svetlana A.,Shashkov, Alexander S.,Granik, Vladimir G.
, p. 15 - 17 (2007/10/03)
The condensation of 3-oxocaprolactam piperidine enamine with 2,6-dibromoquinone and quinone gave 6,8-dibromo-7-hydroxy- and 7-hydroxy-10a-piperidine-2,3,4,5,5a-hexahydro-1H-benzofuro[2,3-c]azepine-1- one adducts, the acid treatment of which afforded novel 9-hydroxy-1,2,3,4-tetrahydro-5H-chromene[3,4-b]pyridine-5-one derivatives.
