37071-20-8Relevant academic research and scientific papers
Some Transformations of 1-(1,2,3,4-Tetranaphthylidene)-Malononitrile or Cyanoacetate
Rajca, Andrzej,Tisler, Miha
, p. 697 - 701 (1990)
Syntheses of 11-amino-5,6-dihydronaphthothienopyrimidine (8) and its 10-oxide 7 from 2-amino-1-cyano-4,5-dihydronaphthothiophene and its derivatives are described.Several open chain tetrahydronaphthylidene derivatives and a substituted pyrimidine derivative 9 were also prepared.
A convenient synthesis of new 2-cyanomethylthieno[3,2-e]1[1,2,4]- triazolo[1,5-c]pyrimidine derivatives
Jabli, Dhiab,Dridi, Khaireddine,El Efrit, Mohamed L.
, p. 403 - 408 (2014/05/20)
A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3- carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors
Dai, Yujia,Guo, Yan,Frey, Robin R.,Ji, Zhiqin,Curtin, Michael L.,Ahmed, Asma A.,Albert, Daniel H.,Arnold, Lee,Arries, Shannon S.,Barlozzari, Teresa,Bauch, Joy L.,Bouska, Jennifer J.,Bousquet, Peter F.,Cunha, George A.,Glaser, Keith B.,Guo, Jun,Li, Junling,Marcotte, Patrick A.,Marsh, Kennan C.,Moskey, Maria D.,Pease, Lori J.,Stewart, Kent D.,Stoll, Vincent S.,Tapang, Paul,Wishart, Neil,Davidsen, Steven K.,Michaelides, Michael R.
, p. 6066 - 6083 (2007/10/03)
A series of novel thienopyrimidine-based receptor tyrosine kinase inhibitors has been discovered. Investigation of structure-activity relationships at the 5- and 6-positions of the thienopyrimidine nucleus led to a series of N,N′-diaryl ureas that potentl
