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Relevant academic research and scientific papers

A four-phenyl porphine preparation method

The invention discloses a preparation method of meso-tetraphenylchlorin. The preparation method comprises the steps that 1, a mixed solution of pyrrole and aromatic aldehyde is prepared for standby; 2, a solvent is added into a polymerization reactor, nitrogen displacement is conducted till the concentration of tail oxygen is lower than 1%, the solvent is heated to backflow, the mixed solution obtained in the first step starts to be dropwise added, a reaction is started, after the mixed solution is dropwise added completely, the reaction is continuously conducted for 0.05 h to 0.5 h, and then the reaction is stopped; 3, oxygen-containing gas with the oxygen volume fraction ranging from 5% to 100% is fed into the polymerization reactor for oxidation, cooling is conducted after the oxidation is completed, filtration is conducted to obtain a filter cake and filtrate, and a product is obtained after the filter cake is washed and dried. The preparation method of the meso-tetraphenylchlorin has the advantages that the yield is high, safety and environmental protection are achieved, separation and purification are easy, and the product quality is stable.

A four-phenyl porphine production method (by machine translation)

The invention discloses a production method for tetraphenyl porphin. The production method includes the steps that 1, pyrrole and aromatic aldehyde are prepared into a mixed solution for standby application; 2, solvent is added into a polymerization reactor, the pressure of the polymerization reactor is maintained at 1-5 atm, the mixed solution obtained in the step 1 starts to be dripped to start a polymerization reaction, after the reaction is finished, reaction products are cooled to normal temperature, and filter liquor and a filter cake are obtained through filtration; 3, the filter cake obtained in the step 2 and propionic acid are added into an oxidation reactor, oxygen-containing gas is introduced to carry out an oxidation reaction, cooling is carried out after oxidation is finished, a solid and filter liquor are obtained through filtration, and the solid is washed and dried to obtain the tetraphenyl porphin. The production method has the advantages of being high in yield, safe and environmentally friendly, separation and purification are easy, and the production quality is stable.

Controlled porphyrinogen oxidation for the selective synthesis of meso-tetraarylchlorins

Chlorins have been synthesized through the reduction of the corresponding porphyrins although theoretically they can be obtained from reduced macrocycle forms as porphyrinogens. A new method for the oxidation of meso- tetraarylporphyrinogens was developed generating a substantial amount of chlorin relatively to porphyrin. The structure of the porphyrinogen, particularly the presence of substituents on the meso-phenyl groups, is decisive for the final yield of chlorin. In the case of meso-tetrakis(2,6-dichlorophenyl)porphyrinogen, 92% of the corresponding chlorin is obtained.

Efficient synthesis of meso-tetraarylporphyrins using i2 as catalyst and ibx as oxidant

meso-Tetraarylporphyrins are synthesized from pyrrole and substituted benzaldehydes by a catalytic amount of I2 as catalyst and o-iodoxybenzoic acid (IBX) as oxidant in two steps and one flask. The advantages of this method include the use of inexpensive and easily available catalyst, avoidance of heavy consumption of CH2Cl2, innocuous oxidant, and good yields.

Novel synthesis of meso-tetraarylporphyrins by using I2 as catalyst and air as oxidant under thermal or UV conditions

An efficient and novel synthesis of meso-tetraarylporphyrins is accomplished through iodine-catalyzed condensation of pyrrole, and aryl aldehydes and subsequent oxidation by air under thermal or ultraviolet (UV) irradiation conditions. The advantages of this procedure include good yields and a green nature. Copyright

IMROVED METHOD FOR SYNTHESIS OF SUBSTUTUTED TETRAPHENYLPORPHINS

Condensation of pyrrole with benzaldehydes in a mixture of xylene and chloroacetic acid gives a series of substituted tetraphenylporphins with yields exeeding the yields of porphyrins synthetized according to known preparative methods.