D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride) is a chemical compound with the molecular formula C8H9Cl2NO2. It is an acetylcholine receptor agonist, specifically a potent and selective agonist for the α7 nicotinic acetylcholine receptor. D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride) has been utilized in research as a tool to study the activity and selectivity of different acetylcholine receptors, and it holds potential for therapeutic applications in various neurological conditions.
37085-27-1
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Basic information
- Product Name: D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)
- Synonyms: D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride);(R)-2-Amino-2-(3-chlorophenyl)acetic acid hydrochloride;(R)-AMINO-(3-CHLORO-PHENYL)-ACETIC ACID HCL;(R)-AMINO-(3-CHLORO-PHENYL)-ACETIC ACID HYDROCHLRIDE;R-3-Chlorophenylglycine hydrochloride (1:1)
- CAS NO:37085-27-1
- Molecular Formula: C8H9Cl2NO2
- Molecular Weight: 222.06856
- EINECS: N/A
- Product Categories: N/A
- Mol File: 37085-27-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Sealed in dry,Room Temperature
- Solubility: N/A
- CAS DataBase Reference: D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)(CAS DataBase Reference)
- NIST Chemistry Reference: D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)(37085-27-1)
- EPA Substance Registry System: D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)(37085-27-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 37085-27-1(Hazardous Substances Data)
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37085-27-1 Usage
Uses
Used in Pharmaceutical Research:D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride) is used as a research tool for studying the activity and selectivity of acetylcholine receptors, particularly the α7 nicotinic acetylcholine receptor. It aids in understanding neurotransmitter systems and receptor pharmacology in the central nervous system.
Used in Neurodegenerative Disease Treatment:
In the field of neurology, D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride) is used as a potential therapeutic agent for the treatment of cognitive deficits and neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Its agonistic effect on the α7 nicotinic acetylcholine receptor suggests a role in improving cognitive function and potentially slowing disease progression.
Used in Cognitive Enhancement Research:
D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride) is also used in cognitive enhancement research, exploring its potential to improve memory and cognitive performance by modulating the activity of acetylcholine receptors in the brain.
Check Digit Verification of cas no
The CAS Registry Mumber 37085-27-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,8 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.Calculate Digit Verification of CAS Registry Number 37085-27:
(7*3)+(6*7)+(5*0)+(4*8)+(3*5)+(2*2)+(1*7)=121
121 % 10 = 1
So 37085-27-1 is a valid CAS Registry Number.
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D-(-)-α-AMino-3-chlorophenylacetyl chloride (hydrochloride)
