37085-55-5Relevant academic research and scientific papers
Novel P1,P2-substituted phosphonate analogues of 2'-deoxyadenosine and 2'-deoxythymidine 5'-triphosphates
Blackburn,Langston
, p. 6425 - 6428 (1991)
P1,P2-Substituted methylene, fluoromethylene, and difluoromethylene analogues of the deoxynucleotides 2'-deoxyadenosine 5'-triphosphate and thymidine 5'-triphosphate have been prepared by reaction between the bisphosphonic acid and t
Process for preparing 2-thiouracil nucleosides
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, (2008/06/13)
Some new 1-(2- or 3-deoxy-β-D-pentofuranosyl)-2-thiouracils and 1-β-D-pentofuranosyl-2-thio-6-azauracils have been prepared. Further, it has been found that the known nucleoside compound, 1-β-D-ribofuranosyl-2-thiouracil is active against Herpes virus and against L-1210 leukemia in mice. An improved method of preparing corresponding 2-0-methyluracil and 2-0-methyl-6-azauracil intermediates is described. The method preserves the β-configuration of the starting nucleoside.
