370852-46-3

Usage

Chemical compound

3-[5-(3-bromophenyl)-1,2,4-oxadiazol-3-yl]Pyridine

Molecular structure

Consists of a pyridine ring attached to a 1,2,4-oxadiazol-3-yl group, which is connected to a 3-bromophenyl group

Potential applications

Pharmaceuticals, agrochemicals, materials science

Pharmacological activities

May have potential pharmacological activities for use in drug development

Organic synthesis

Can be used as a building block in organic synthesis

Chemical intermediate

Potential as a chemical intermediate in the production of other compounds

Research and testing

Further research and testing needed to fully understand potential uses and applications

Upstream product

• 585-76-2 m-bromobenzoic acid 
• 1594-58-7 N-hydroxy-3-pyridinecarboximidamide 
• 100-54-9 pyridine-3-carbonitrile 

Downstream Products

• 1033725-47-1 tert-butyl 4-(3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)phenyl)piperazine-1-carboxylate 
• 1033725-48-2 tert-butyl (R)-2-(3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)phenyl)pyrrolidine-1-carboxylate 
• 1033724-52-5 1-(3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)phenyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Continuous-flow synthesis of highly functionalized imidazo-oxadiazoles facilitated by microfluidic extraction

A versatile continuous-flow synthesis of highly functionalized 1,2,4-oxadiazoles starting from carboxylic acids is reported. This process was applied to the multistep synthesis of imidazo[1,2-a]pyridin-2-yl-1,2,4-oxadiazoles, using a three reactor, multistep continuous-flow system without isolation of intermediates. This continuous-flow method was successfully combined with a single-step liquid-liquid microextraction unit to remove high boiling point polar solvents and impurities and provides the target compounds in high purity with excellent overall yields.

NOVEL 1,2,4 OXADIAZOLE COMPOUNDS AND METHODS OF USE THEREOF

The invention relates to 1,2,4 oxadiazole compounds and analogs thereof, represented by formula (II), and compositions and methods of use thereof.

PHARMACEUTICAL COMPOSITIONS AND THEIR METHODS OF USE

The invention relates to a composition comprising a neuronal nicotinic receptor ligand and an α4β2 positive allosteric modulator, a method of using the same, and a related article of manufacture.