370856-37-4Relevant articles and documents
In vitro and in vivo activities of oligodeoxynucleotide-based thrombin inhibitors containing neutral formacetal linkages
He, Gong-Xin,Williams, John P.,Postich, Michael J.,Swaminathan,Shea, Regan G.,Terhorst, Terry,Law, Veronica S.,Mao, Cheri T.,Sueoka, Cathy,Coutré, Steven,Bischofberger, Norbert
, p. 4224 - 4231 (2007/10/03)
A series of 15-mer oligodeoxynucleotide analogues were synthesized, and their thrombin inhibitory activities in vitro and in vivo were evaluated. These oligodeoxynucleotide analogues share the same sequence (GGTTGGTGTGGTTGG) but have one or more phosphodi