37091-33-1 Usage
Uses
Used in Pharmaceutical Industry:
1-[3-(4-CHLOROPHENYL)-5-ISOXAZOLYL]-1-ETHANONE is used as a potent opioid analgesic for the management of severe pain, particularly in cases where other pain relief options are insufficient. Its high potency allows for effective pain control at lower doses compared to other opioids, although this also contributes to its high potential for abuse and addiction.
Used in Research and Development:
In the scientific community, 1-[3-(4-CHLOROPHENYL)-5-ISOXAZOLYL]-1-ETHANONE serves as a valuable research compound for studying the mechanisms of opioid action, addiction, and the development of potential treatments for opioid dependence. Its structural similarity to fentanyl and other opioids makes it an important tool in understanding the nuances of opioid receptor interactions and the development of safer and more effective analgesics.
Check Digit Verification of cas no
The CAS Registry Mumber 37091-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,9 and 1 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37091-33:
(7*3)+(6*7)+(5*0)+(4*9)+(3*1)+(2*3)+(1*3)=111
111 % 10 = 1
So 37091-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H8ClNO2/c1-7(14)11-6-10(13-15-11)8-2-4-9(12)5-3-8/h2-6H,1H3
37091-33-1Relevant academic research and scientific papers
A facile one-pot synthesis of 3,5-disubstituted isoxazole derivatives using hydroxy (tosyloxy) iodobenzene
Jadhav, Ravindra D.,Mistry, Hitesh D.,Motiwala, Hashim,Kadam, Kishorkumar S.,Kandre, Shivaji,Gupte, Amol,Gangopadhyay, Ashok K.,Sharma, Rajiv
, p. 774 - 780 (2013/08/23)
Hydroxy (tosyloxy) iodobenzene (HTIB), a hypervalent iodine reagent, has been extensively used for oxidative transformations. We have developed a one-pot synthesis wherein aldoximes when reacted with alkynes in the presence of HTIB result in the direct formation of isoxazoles. This simple and straightforward reaction allows for ease of purification while leading to the formation of high purity 3,5-disubstituted isoxazoles in moderate yields.
In search of new chemical entities with spermicidal and anti-HIV activities
Srivastava, Seema,Bajpai, Lakshmi Kant,Batra, Sanjay,Bhaduri, Amiya P.,Maikhuri,Gupta, Gopal,Dhar
, p. 2607 - 2613 (2007/10/03)
Several compounds belonging to 2-isoxazolines (4,5a-c), isoxazoles (3,6a-c) and 1-amino-1-cycloalkyl-2-substituted phenyl ethanes (16-18,a-e) have been synthesised and found to possess spermicidal activity. Out of these a couple of compounds (5a and 6a) exhibit anti-HIV activity. (C) Elsevier Science Ltd.
