37098-46-7Relevant academic research and scientific papers
Arynes in the Monoarylation of Unprotected Carbohydrate Amines
Pal, Kumar Bhaskar,Mahanti, Mukul,Nilsson, Ulf J.
, p. 616 - 619 (2018)
A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderate to good yields with broad scope.
