37112-54-2

Upstream product

• 149-30-4 2-Mercaptobenzothiazole 
• 615-21-4 1,3-benzothiazol-2-ylhydrazine 
• 3673-45-8 4-nitrobenzaldehyde 2-(2-benzothiazolyl)hydrazone 
• 546-67-8 lead(IV) tetraacetate 
• 37120-70-0 N'-benzothiazol-2-yl-4-nitro-benzohydrazonoyl bromide 

Relevant academic research and scientific papers

Thallium(III) salts mediated oxidative cyclization of arenecarbaldehyde benzothiazol-2-ylhydrazones to bridged head nitrogen heterocycles

Oxidation of arenecarbaldehydebenzothiazol-2-ylhydrazones (4) with thallium (III) acetate in refluxing acetic acid, thallium (III) acetate and thallium (III) nitrate in acetonitrile in presence of p-toluene sulphonic acid afforded 3-aryl-1,2,4-triazolo [3

Synthesis of new triazolo and pyrazolo benzothiazoles

Benzothiazole-2-thiol 1 on heating with excess of hydrazine hydrate yields 2-hydrazino-1,3-benzothiazole (2). Compound 2 on reaction with carbon disulfide in alkaline medium affords [1,2,4] triazolo [3,4-b] [1,3] benzothiazole-3-thiol (3). Condensation of 2 with various substituted aryl aldehydes yields corresponding hydrazine derivatives (4), which on cyclisation with acetic anhydride gave corresponding [1,2,4] triazolo [3,4-6] [1,3] benzothiazoles (5). Some other triazolo derivatives (6,7,8) of benzothiazole were obtained by the cyclization of 2 with benzoyl chloride, acetyl chloride and formic acid respectively. Again compound 2 on condensation with acetyl acetone and ethylacetoacetate gives pyrazolo derivatives (9,10) respectively. The synthesized compounds were characterized by elemental and spectral analysis.