37118-22-2Relevant academic research and scientific papers
Cu-Catalyzed Oxidative-Reaction of Tosylmethylisocyanide and Benzyl Alcohols: Efficient Synthesis of 4-(tert-butylperoxy)-5-aryloxazol-2(3H)-ones and 5-Aryloxazol-2(5H)-ones
Sepahvand, Heshmatollah,Bazgir, Ayoob,Shaabani, Ahmad
, p. 2068 - 2075 (2020/01/28)
Herein, a novel copper-catalyzed reaction of tosylmethylisocyanide (TosMIC) with benzyl alcohols has been developed using tert-butyl hydroperoxide (TBHP) for the first time. The reaction involves the in-situ oxidation of benzyl alcohol to corresponding be
Tandem oxidative isocyanide-based cycloaddition reactions in the presence of MIL-101(Cr) as a reusable solid catalyst
Shaabani, Ahmad,Sepahvand, Heshmatollah,Amini, Mostafa M.,Hashemzadeh, Alireza,Borjian Boroujeni, Mahmoud,Badali, Elham
, p. 1832 - 1837 (2018/03/07)
The tandem oxidative three-component synthesis of two types of the heterocycles such as furans and imidazopyridines, via isocyanides [1+4] cycloaddition reactions in the presence of MIL-101(Cr) under aerobic conditions are reported. When the 4-toluenesulfonylmethyl isocyanide was used, an unexpected [3+2] cycloaddition reaction of isocyanides with aldehydes accomplished and dihydrophenyloxazoles and phenyloxazoles produced. These syntheses were successfully carried out using a wide scope of the substrates.
A Mild and convenient synthesis of 4-tosyl-4,5-dihydrooxazoles
Companyo, Xavier,Moyano, Albert,Rios, Ramon
experimental part, p. 293 - 296 (2010/04/23)
A facile and mild synthesis of 4-tosyl-4,5-dihydrooxazoles is described. The reaction between tosyl methyl isocyanide (TosMIC) and cinnamic or aromatic aldehydes is catalyzed by triethylamine, affording trans-5-styryl- or 5-aryl-4-tosyl-4,5-dihydrooxazole
ARENE-CHROMIUM-TRICARBONYL COMPLEXES: STEREOSELECTIVE REACTIONS WITH ISOCYANIDE
Solladie-Cavallo, A.,Quazzotti, S.,Colonna, S.,Manfredi, A.
, p. 2933 - 2936 (2007/10/02)
More than 98 percent of A.I. is obtained during addition of TosMic with chiral complexes 2 and 3.The diastereoselectivity of the formation of the oxazolines is studied and the diastereomers clearly assigned.Orbital-interactions and electronic repulsions s
