3715-08-0Relevant articles and documents
Synthesis of carbon-14 labelled gemifloxacin
Shin, Hyun Il,Rim, Jong Gill,Lee, Ki Seung,Kim, Young Seok,Nam, Do Hyun,Shin, Hyun Ik,Chang, Jay Hyok,Oh, Chang Young,Ham, Won Hun
, p. 779 - 786 (2004)
A new antibacterial agent gemifloxacin was labelled with carbon-14 for studies of pharmacokinetics and metabolism, the label was located in position 3 of the quinolone ring system. The overall radiochemical yield of the 14-step synthesis, starting from [2-14C]sodium acetate was 16.6%, and the radiochemical purity 97.5%.