37165-30-3Relevant academic research and scientific papers
Lipase Mediated Optical Resolution of Bicyclic Secondary Carbinols
Meltz, Morgan,Saccomano, Nicholas A.
, p. 1201 - 1202 (1992)
The optical resolution of (+/-)-endo-bicycloheptan-2-ol and (+/-)-bicyclooctan-2-ol proceeds by porcine lipase catalyzed transesterification under anhydrous conditions.
A crystalline, internally-coordinated chloroborane for asymmetric hydroboration
von Dollen, Breanna,Wood, John L.,Savage, Quentin R.,Jones, Andrew J.,Garner, Charles M.
supporting information, (2022/02/01)
Asymmetric hydroboration is an important method in the preparation of enantiomerically-enriched compounds that are necessary in many areas of chemistry. Here is reported the preparation of a unique chiral chloroborane-internal ether complex and its applic
Asymmetric Functionalization of Bicycloalkenes by Catalytic Enantioposition-Selective Hydrosilylation
Uozumi, Yasuhiro,Lee, Sang-Yong,Hayashi, Tamio
, p. 7185 - 7188 (2007/10/02)
Hydrosilylation of norbornene with trichlorosilane in the presence of palladium catalyst (0.01-0.1 mol percent) coordinated with (R)-MOP ligand gave a quantitative yield of exo-2-trichlorosilylnorbornane, which was oxidized with hydrogen peroxide to give (1S,2S,4R)-exo-2-norbornanol in 96percent ee.The similar hydrosilylation and oxidation of endo-5,6-dicarbomethoxy-2-norbornene, bicyclooctene, and norbornadiene gave the corresponding bicyclic alcohols of 94percent ee, 92percent ee, and 95percent ee, respectively.
Microbial Stereodifferentiating Reduction of Carbonyl Compounds; Proposed Quadrant Rule
Nakazaki, Masao,Chikamatsu, Hiroaki,Naemura, Koichiro,Asao, Masaaki
, p. 4432 - 4440 (2007/10/02)
The stereochemistry of the isomeric alcohols obtained from microbial reduction (Curvularia lunata and Rhodotorula rubra) of the racemic modification of bicyclic (5,8,23), benzobicyclic (11,14,17), and tricyclic(20) ketones with a wide variation in molecular framework has led to the formulation of a quadrant rule which provides information on the absolute configuration of the substrate ketone.
