3717-88-2

Basic information

• Product Name: Flavoxate hydrochloride
• Synonyms: 1-piperidineethanol,3-methyl-4-oxo-2-phenyl-4h-1-benzopyran-8-carboxylate,h;2-piperidinoethyl-3-methyl-4-oxo-2-phenyl-4h-1-benzopyran-8-carboxylatehydro;3-methyl-4-oxo-2-phenyl-4h-1-benzopyran-8-carboxylicaci2-piperidinoethyl;bladderon;flaroxatehydrochloride;genurin;nsc-114649;piperidinoethyl-3-methylflavone-8-carboxylatehydrochloride
• CAS NO: 3717-88-2
• Molecular Formula: C24H26ClNO4
• Molecular Weight: 427.92
• EINECS: 223-066-4
• Product Categories: ACTIVE PHARMACEUTICAL INGREDIENTS;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API
• Mol File: 3717-88-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 232-234°C
• Boiling Point: 564.1 °C at 760 mmHg
• Flash Point: 294.9 °C
• Appearance: white/solid
• Density: 1.203 g/cm³
• Vapor Pressure: 9.56E-13mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: H2O: ~6.6 mg/mL
• CAS DataBase Reference: Flavoxate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Flavoxate hydrochloride(3717-88-2)
• EPA Substance Registry System: Flavoxate hydrochloride(3717-88-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• WGK Germany: 3
• RTECS: DJ2450000
• Hazardous Substances Data: 3717-88-2(Hazardous Substances Data)

Usage

Chemical Properties

Flavoxate hydrochloride is Crystalline Solid

Uses

Different sources of media describe the Uses of 3717-88-2 differently. You can refer to the following data:
1. Flavoxate hydrochloride is used as antispasmodic; in treatment of urinary incontinence
2. Antispasmodic;Phosphodiesterase inhibitor

Definition

ChEBI: The hydrochloride salt of flavoxate.

Therapeutic Function

Spasmolytic

Veterinary Drugs and Treatments

Flovoxate may be considered for treating dogs with detrusor hyperspasticity (hyperactive bladder, urge incontinence).

InChI:InChI=1/C24H25NO4.ClH/c1-17-21(26)19-11-8-12-20(23(19)29-22(17)18-9-4-2-5-10-18)24(27)28-16-15-25-13-6-3-7-14-25;/h2,4-5,8-12H,3,6-7,13-16H2,1H3;1H

Upstream product

• 90101-87-4 Methyl 3-methylflavone-8-carboxylate 
• 3468-01-7 3-methylflavone-8-carboxylic acid 
• 100859-97-0 piperidinoethyl chloride 

Downstream Products

• 3468-01-7 3-methylflavone-8-carboxylic acid 

Relevant articles and documents

METHODS FOR TREATING CHRONIC FATIGUE SYNDROME AND MYALGIC ENCEPHALOMYELITIS

In one aspect the invention relates to a method of treatment selected from the group consisting of: (a) treating a symptom such as pain in a subject identified or diagnosed as having Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS); (b) treating a symptom such as pain in a subject having dysfunctional TRPM3 ion channel activity; (c) restoring NK cell function in a subject having dysfunctional TRPM3 ion channel activity; and (d) restoring calcium homeostasis in a subject having dysfunctional TRPM3 ion channel activity. The method comprises the step of administering to the subject a therapeutically effective amount of at least one therapeutic compound selected from the group consisting of: (i) an opioid receptor antagonist; (ii) an opioid antagonist; and (iii) a therapeutic compound that restores TRPM3 ion channel activity. In some embodiments the therapeutic compound is naltrexone hydrochloride.