3718-59-0Relevant academic research and scientific papers
Lanthanide replacement in organic synthesis: Luche-type reduction of α,β-unsaturated ketones in the presence of calcium triflate
Forkel, Nina V.,Henderson, David A.,Fuchter, Matthew J.
supporting information; scheme or table, p. 2129 - 2132 (2012/09/08)
Development of a calcium-mediated regioselective 1,2-reduction of challenging α,β-unsaturated ketones, such as 2-cyclopententone, is reported. The corresponding allylic alcohols are obtained in very good regioselectivities using Ca(OTf)2 and NaBH4. Furthermore, we have shown that our method can stereoselectively reduce aziridinyl ketones.
Substituent Effect Behavior in the Antiaromatic Inden-1-yl Cation System
Friedrich, Edwin C.,Tam, Teresa M.
, p. 315 - 319 (2007/10/02)
Studies of the rate-accelerating effects in solvolysis produced by 5-methyl and 5-methoxy substituents on the benzene ring and a 3-methyl substituent on the double bond of the inden-1-yl 3,5-dinitrobenzolate system have been carried out.In both 80percent aqueous acetone and in 2,2,2-trifluoroethanol, the rate accelerations observed in the inden-1-yl system were approximately the same as those found in model cyclopenten-3-yl and indan-1-yl systems.From these results, it is concluded that delocalization of charge into both the benzene ring and double bond of the 8?-electron inden-1-yl carbocation is taking place and is apparently undiminished by antiaromatic effects.
