37180-86-2Relevant academic research and scientific papers
Design of Manganese Phenol Pi-complexes as Shvo-type Catalysts for Transfer Hydrogenation of Ketones
Shvydkiy, Nikita V.,Vyhivskyi, Oleksandr,Nelyubina, Yulia V.,Perekalin, Dmitry S.
, p. 1602 - 1605 (2019)
Catalytic hydrogenation is one of the most important reactions both in academic research and industry. We explored ability of the manganese pi-complexes to act as Shvo-type catalysts for transfer hydrogenation of ketones. DFT calculations suggested that the transfer of hydrogen atoms from the hypothetical intermediate [(C6Me3H2OH)Mn(CO)2H] to acetone has low activation barrier of 10.9 kcal mol?1. Experimentally a number of ketones with various functional groups (OMe, NH2, Cl, CF3, pyridyl) were successfully reduced in isopropanol at 90 °C in the presence of the complex [(C6Me3H2OH)Mn(CO)3]BF4 (1 mol %) and tBuOK (75 mol %). However, further investigation revealed that the reduction was mainly promoted by base rather than the manganese complex.
