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3-Fluoropropyl-1-methanesulfonate, with the chemical formula C4H9FO3S, is a clear, colorless liquid that serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. It is primarily recognized for its role as a reagent in the selective fluorination of organic compounds, which is a critical process in the development of various chemical products.

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  • 372-04-3 Structure
  • Basic information

    1. Product Name: 3-FLUOROPROPYL-1-METHANESULFONATE
    2. Synonyms: 3-Fluoropropylmethanesulphonate98%;3-fluoropropyl methanesulfonate;methanesulfonic acid 3-fluoropropyl ester;3-Fluoroprop-1-yl methanesulphonate 98%;3-FLUOROPROPYL-1-METHANESULFONATE;3-FLUOROPROPYL-1-METHANESULPHONATE;3-Fluoropropyl methanesulphonate;3-Fluoropropyl methanesulphonate 98%
    3. CAS NO:372-04-3
    4. Molecular Formula: C4H9FO3S
    5. Molecular Weight: 156.18
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 372-04-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 116/15mm
    3. Flash Point: 108.9°C
    4. Appearance: /
    5. Density: 1.225g/cm3
    6. Vapor Pressure: 0.0247mmHg at 25°C
    7. Refractive Index: 1.405
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 3-FLUOROPROPYL-1-METHANESULFONATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-FLUOROPROPYL-1-METHANESULFONATE(372-04-3)
    12. EPA Substance Registry System: 3-FLUOROPROPYL-1-METHANESULFONATE(372-04-3)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 372-04-3(Hazardous Substances Data)

372-04-3 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-Fluoropropyl-1-methanesulfonate is used as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its ability to selectively fluorinate organic compounds makes it a valuable tool in the creation of molecules with specific properties and enhanced efficacy.
Used as a Reagent in Organic Synthesis:
In the field of organic synthesis, 3-Fluoropropyl-1-methanesulfonate is utilized as a reagent for the selective fluorination of organic compounds. This selective fluorination is crucial for the synthesis of complex organic molecules with desired properties, such as improved biological activity or chemical stability.
Used as a Solvent in Organic Synthesis:
3-Fluoropropyl-1-methanesulfonate also serves as a solvent in organic synthesis, facilitating various chemical reactions. Its unique properties as a solvent can enhance the efficiency and selectivity of reactions, leading to the production of high-quality products.
Used as a Stabilizer in Polymer Production:
In the polymer industry, 3-Fluoropropyl-1-methanesulfonate is employed as a stabilizer in the production of polymers. Its stabilizing properties help to improve the quality and performance of the resulting polymers, ensuring their durability and resistance to degradation.
Safety Precautions:
Given its classification as a hazardous chemical, 3-Fluoropropyl-1-methanesulfonate requires careful handling. It may cause skin and eye irritation, and is harmful if swallowed or inhaled. To ensure safety, it should be stored and used in a well-ventilated area, and proper personal protective equipment, such as gloves, goggles, and respirators, should be worn when handling this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 372-04-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,7 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 372-04:
(5*3)+(4*7)+(3*2)+(2*0)+(1*4)=53
53 % 10 = 3
So 372-04-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H9FO3S/c1-9(6,7)8-4-2-3-5/h2-4H2,1H3

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