372163-84-3 Usage
Chemical structure
A complex organic molecule with a core structure containing a furo[2,3-g]indazole ring system and an ethyl group attached to it.
Functional groups
Contains a propan-2(S)-amine group, which is a derivative of propane with an amine functional group.
Stereochemistry
The compound is a chiral molecule, with the (S) configuration indicating the stereochemistry of the propan-2-amine group.
Potential applications
May have potential applications in pharmaceuticals or as a research tool in the field of organic chemistry due to its unique structure and potential biological activity.
Molecular weight
Approximately 292.38 g/mol (calculated from the molecular formula)
Solubility
Not specified in the provided material, but as an amine, it may be soluble in polar solvents like water or alcohol.
Stability
Not specified in the provided material, but the stability of the compound may depend on factors such as temperature, pH, and exposure to light or air.
Reactivity
Not specified in the provided material, but the compound may react with acids, bases, or other reactive species due to the presence of the amine functional group.
Synthesis
Not specified in the provided material, but the synthesis of 1-(7-Ethyl-1H-furo[2,3-g]indazol-1-yl)propan-2(S)-amine may involve the formation of the furo[2,3-g]indazole ring system, followed by the attachment of the ethyl group and the propan-2(S)-amine group.
Check Digit Verification of cas no
The CAS Registry Mumber 372163-84-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,2,1,6 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 372163-84:
(8*3)+(7*7)+(6*2)+(5*1)+(4*6)+(3*3)+(2*8)+(1*4)=143
143 % 10 = 3
So 372163-84-3 is a valid CAS Registry Number.
372163-84-3Relevant academic research and scientific papers
Synthesis and structure-activity relationships of a series of substituted 2-(1H-furo[2,3-g]indazol-1-yl)ethylamine derivatives as 5-HT2C receptor agonists
Shimada, Itsuro,Maeno, Kyoichi,Kazuta, Ken-ichi,Kubota, Hideki,Kimizuka, Tetsuya,Kimura, Yasuharu,Hatanaka, Ken-ichi,Naitou, Yuki,Wanibuchi, Fumikazu,Sakamoto, Shuichi,Tsukamoto, Shin-ichi
, p. 1966 - 1982 (2008/09/21)
A series of novel indazole derivatives were synthesized, and their structure-activity relationships examined in order to identify potent and selective 5-HT2C receptor agonists. Among these compounds, (S)-2-(7-ethyl-1H-furo[2,3-g]indazol-1-yl)-1-methylethylamine (YM348) had a good in vitro profile, that is, high agonistic activity to the human 5-HT2C receptor subtype (EC50 = 1.0 nM) and high selectivity over 5-HT2A receptors. This compound was also effective in a rat penile erection model when administered po.
