37228-65-2

Basic information

• Product Name: SARCOSINE DEHYDROGENASE
• Synonyms: SARCOSINE DEHYDROGENASE;SARCOSINE: [ACCEPTOR] OXIDOREDUCTASE [DEMETHYLATING];EC 1.5.99.1;sarcosine dehydrogenase from*pseudomonas sp.;Dehydrogenase, sarcosine;frompseudomonassp.
• CAS NO: 37228-65-2
• Molecular Weight: 0
• EINECS: 253-414-0
• Mol File: 37228-65-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: SARCOSINE DEHYDROGENASE(CAS DataBase Reference)
• NIST Chemistry Reference: SARCOSINE DEHYDROGENASE(37228-65-2)
• EPA Substance Registry System: SARCOSINE DEHYDROGENASE(37228-65-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 37228-65-2(Hazardous Substances Data)

Usage

Description

Sarcosine dehydrogenase is an enzyme that plays a crucial role in the metabolism of glycine and choline. It catalyzes the oxidation of sarcosine to glycine, using the coenzyme FAD as a cofactor, and generating formaldehyde and hydrogen peroxide as by-products. This enzyme is primarily found in the liver and kidney, where it is involved in the detoxification of sarcosine and the production of glycine, an important amino acid for protein synthesis and neurotransmission. Dysregulation of sarcosine dehydrogenase activity has been associated with certain metabolic disorders and disease states, making it an important target for therapeutic interventions and drug development.

Uses

Used in Pharmaceutical Industry:
Sarcosine dehydrogenase is used as a target for therapeutic interventions and drug development for the treatment of metabolic disorders and disease states associated with its dysregulation.
Used in Research and Development:
Sarcosine dehydrogenase is used as a subject of research to better understand its role in the metabolism of glycine and choline, as well as its involvement in detoxification processes and protein synthesis. This knowledge can contribute to the development of new treatments and therapies for related conditions.