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Wilfortrine is a naturally occurring chemical compound that belongs to the class of pyrrolizidine alkaloids, predominantly found in plants of the Senecio and Crotalaria species. It is recognized for its potential toxic effects on the liver, particularly when ingested by animals or humans, leading to hepatotoxicity and carcinogenicity due to its ability to cause liver damage and disrupt the organ's normal functioning. The presence of wilfortrine in herbal remedies and dietary supplements is a significant concern, emphasizing the need for understanding and monitoring its occurrence in natural products to avert potential harm to human health.

37239-48-8

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37239-48-8 Usage

Uses

Used in Pharmaceutical and Toxicological Research:
Wilfortrine is utilized as a subject of study in pharmaceutical and toxicological research to understand its hepatotoxic and carcinogenic properties. This research is crucial for developing methods to mitigate or counteract its harmful effects and to ensure the safety of herbal remedies and dietary supplements that may contain wilfortrine.
Used in Regulatory and Quality Control:
Wilfortrine is used as a marker in regulatory and quality control processes to monitor and regulate the presence of this potentially harmful compound in natural products, ensuring that they meet safety standards and do not pose a risk to human health.
Used in Education and Awareness:
Wilfortrine serves as a case study in educational programs and awareness campaigns about the potential risks associated with certain natural products, particularly those containing pyrrolizidine alkaloids. This helps to inform consumers and professionals about the importance of proper identification, preparation, and use of natural products to prevent adverse health effects.

Check Digit Verification of cas no

The CAS Registry Mumber 37239-48-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,2,3 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 37239-48:
(7*3)+(6*7)+(5*2)+(4*3)+(3*9)+(2*4)+(1*8)=128
128 % 10 = 8
So 37239-48-8 is a valid CAS Registry Number.

37239-48-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Wilfortrine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37239-48-8 SDS

37239-48-8Downstream Products

37239-48-8Relevant academic research and scientific papers

Sesquiterpene alkaloids from Tripterygium wilfordii (Hook): A nuclear magnetic resonance study of 1-desacetylwilfordine, 1-desacetylwilfortrine, and 2-debenzoyl-2-nicotinoylwilforine

Ya,Strunz,Calhoun

, p. 371 - 374 (2007/10/02)

1-Desacetylwilfordine, 8, 1-desacetylwilfortrine, 9, and 2-debenzoyl-2-nicotinoylwilforine, 10, have been isolated from root extracts of the Chinese medicinal and insecticidal plant Tripterygium wilfordii. Analysis of the 1H and 13C

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