372482-05-8

Basic information

• Product Name: (3R,4R)-1-benzyl-3-(tert-butyldimethylsilyl)oxy-4-hydroxypyrrolidine
• CAS NO: 372482-05-8
• Molecular Weight: 307.508
• Mol File: 372482-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-1-benzyl-3-(tert-butyldimethylsilyl)oxy-4-hydroxypyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-1-benzyl-3-(tert-butyldimethylsilyl)oxy-4-hydroxypyrrolidine(372482-05-8)
• EPA Substance Registry System: (3R,4R)-1-benzyl-3-(tert-butyldimethylsilyl)oxy-4-hydroxypyrrolidine(372482-05-8)

Safety Data

• Hazardous Substances Data: 372482-05-8(Hazardous Substances Data)

Upstream product

• 187032-53-7 (3S,4S)-1-N-benzyl-3,4-dihydroxypyrrolidine-2,6-dione 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant articles and documents

Efficient stereospecific synthesis of (S,S)-3-methoxy-4-methylaminopyrrolidine

Efficient stereospecific synthesis of (S,S)-3-methoxy-4-methylaminopyrrolidine, an important intermediate for a novel quinolone antitumor agent AG-7352 is presented. Starting from either D- or L-tartaric acid, a stereospecific synthesis of the chiral pyrrolidine was achieved via two SN2 displacement reactions. From the results of this synthetic study, the absolute structure of AG-7352 was chemically determined.