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1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxamide is an off-white solid that serves as an intermediate in the preparation of Citalopram, a widely prescribed antidepressant medication.

372941-46-3

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372941-46-3 Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxamide is used as a chemical intermediate for the synthesis of Citalopram, an antidepressant drug. Its role in the pharmaceutical industry is crucial for the production of medications that help alleviate symptoms of depression and anxiety.
As an intermediate, it contributes to the development of Citalopram by facilitating the chemical reactions required to create the final product. 1-(4-Fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarboxamide plays a significant role in the pharmaceutical industry, as it is a key component in the manufacturing process of an essential medication for mental health treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 372941-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,2,9,4 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 372941-46:
(8*3)+(7*7)+(6*2)+(5*9)+(4*4)+(3*1)+(2*4)+(1*6)=163
163 % 10 = 3
So 372941-46-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H10FNO3/c16-10-4-1-8(2-5-10)13-11-6-3-9(14(17)18)7-12(11)15(19)20-13/h1-7,13H,(H2,17,18)

372941-46-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-fluorophenyl)-3-oxo-1H-2-benzofuran-5-carboxamide

1.2 Other means of identification

Product number -
Other names 1-(4-Fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:372941-46-3 SDS

372941-46-3Relevant academic research and scientific papers

Method for the preparation of citalopram

-

, (2008/06/13)

A method for the preparation of citalopram comprising reaction of a compound of formula 5-aminomethyl-1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran with an oxidising agent to prepare citalopram.

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