37296-80-3 Usage
Uses
Used in Pharmaceutical Industry:
Colestipol hydrochloride is used as a cholesterol-lowering agent for the treatment of type II hyperlipoproteinemias. It works by binding bile acids in the intestine, preventing their reabsorption, and thus reducing cholesterol levels in the body.
Used in Research Applications:
Colestipol hydrochloride is used as a study aid in pharmacokinetic research, such as in combination with Teriflunomide (A771726), to understand the drug's interaction and effectiveness in the body.
Clinical Use
#N/A
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of
coumarins and phenindione.
Ciclosporin: no reports of an interaction; however,
ciclosporin levels should be carefully monitored if
colestipol and ciclosporin are prescribed concurrently,
as colestipol may interfere with ciclosporin
absorption.
Metabolism
Not applicable as colestipol is not systemically absorbed.
Check Digit Verification of cas no
The CAS Registry Mumber 37296-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,2,9 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 37296-80:
(7*3)+(6*7)+(5*2)+(4*9)+(3*6)+(2*8)+(1*0)=143
143 % 10 = 3
So 37296-80-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H23N5.ClH/c9-1-3-11-5-7-13-8-6-12-4-2-10;/h11-13H,1-10H2;1H
