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Elaiophylin, a macrodiolide antibiotic, is a highly characteristic metabolite produced by Streptomyces hygroscopicus. It is isolated from various strains of Streptomyces and has a unique structure that contributes to its diverse biological activities.

37318-06-2

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37318-06-2 Usage

Uses

Used in Pharmaceutical Industry:
Elaiophylin is used as an inhibitor of testosterone 5-reductase for its potential application in treating conditions related to hormonal imbalances.
Used in Antifungal Applications:
Elaiophylin is used synergistically with its co-metabolite, rapamycin, to enhance antifungal activity, particularly against Candida species.
Used in Anthelmintic Applications:
Elaiophylin is used as an anthelmintic agent to combat parasitic worm infections.
Used in Immunosuppressive Applications:
Elaiophylin is used for its immunosuppressive activity, which may have potential applications in the treatment of autoimmune diseases and transplantation medicine.
Used in Inhibiting NO Synthesis:
Elaiophylin is used to inhibit nitric oxide (NO) synthesis, which may have implications in the treatment of conditions involving excessive NO production, such as certain inflammatory diseases.
Used in Antimicrobial Applications:
Elaiophylin displays broad, albeit weak, biological activity against bacteria, nematodes, protozoa, and mammalian tumor cells, making it a potential candidate for the development of new antimicrobial agents.
Used in Anti-protozoal Applications:
Elaiophylin is used for its in vitro anti-protozoal activity against Plasmodium and Trypanosoma species, which could be useful in the treatment of parasitic infections such as malaria and trypanosomiasis.
Used in Ion Channel Research:
Elaiophylin is used in the formation of stable, long-lasting cation-selective ion channels in bilayer membranes, which may have applications in the study of ion channel function and the development of ion channel modulators.

Check Digit Verification of cas no

The CAS Registry Mumber 37318-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,3,1 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 37318-06:
(7*3)+(6*7)+(5*3)+(4*1)+(3*8)+(2*0)+(1*6)=112
112 % 10 = 2
So 37318-06-2 is a valid CAS Registry Number.
InChI:InChI=1/C54H88O18/c1-13-37-33(9)71-53(63,25-41(37)67-45-23-39(55)49(61)35(11)65-45)31(7)47(59)29(5)51-27(3)19-15-17-22-44(58)70-52(28(4)20-16-18-21-43(57)69-51)30(6)48(60)32(8)54(64)26-42(38(14-2)34(10)72-54)68-46-24-40(56)50(62)36(12)66-46/h15-22,27-42,45-52,55-56,59-64H,13-14,23-26H2,1-12H3/b19-15+,20-16+,21-18+,22-17+/t27-,28-,29-,30-,31-,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42+,45-,46-,47+,48+,49+,50+,51-,52-,53+,54+/m0/s1

37318-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name elaiophylin

1.2 Other means of identification

Product number -
Other names azalomycin B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37318-06-2 SDS

37318-06-2Upstream product

37318-06-2Relevant academic research and scientific papers

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