37326-33-3 Usage
Uses
Used in Medical Applications:
Hyaluronidase is used as a facilitator for the absorption of fluid into tissues, promoting the diffusion of local anesthetics and enhancing the effects of anticancer drugs.
Used in Flow Cytometry:
Hyaluronidase is used as a reagent in flow cytometry, aiding in the isolation of putative spermatogonial stem cells (SSCs) and studying the effects of magnetic stimulation in magnetic hydrogel properties.
Used in Tissue Isolation:
Hyaluronidase is used as a reagent for the isolation of specific cell types, such as group-III auditory neurons of Muller's organ, for patch-clamp recordings.
Used in Immunohistochemistry:
Hyaluronidase is used as a reagent in immunohistochemistry to visualize the distribution of collagen type II.
Used in Hydrogel Degeneration:
Hyaluronidase is used as a reagent for the degeneration of hydrogels, which can be useful in various research applications.
Used in Pharmaceutical Industry:
Hyaluronidase is used as an enzyme in the pharmaceutical industry for its ability to reduce the viscosity of connective tissues and promote tissue penetration.
Chemical Properties:
Hyaluronidase is a white or yellowish-white, amorphous powder.
Biochem/physiol Actions
Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression.
Purification Methods
Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.]
Check Digit Verification of cas no
The CAS Registry Mumber 37326-33-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,3,2 and 6 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 37326-33:
(7*3)+(6*7)+(5*3)+(4*2)+(3*6)+(2*3)+(1*3)=113
113 % 10 = 3
So 37326-33-3 is a valid CAS Registry Number.