373385-95-6Relevant academic research and scientific papers
Solid-phase synthesis of β-Amino ketones and six-ring carbamates via immobilized α-alkoxycarbonylamino sulfones
Schunk, Stefan,Enders, Dieter
, p. 3177 - 3180 (2001)
(figure presented) β-Amino ketones and substituted 1,3-oxazinan-2-ones have been synthesized utilizing polymer-bound and carbamate-linked α-alkoxycarbonylamino sulfones. Key steps in the synthesis are the immobilization of the N-acylimine precursor, the Mannich-type addition of various nucleophiles, and the diastereoselective reduction of the resin-bound ketone.
