373387-60-1Relevant academic research and scientific papers
Stereospecific Protodeauration/Transmetalation Generating Configurationally Stable P-Metalated Nucleoside Derivatives
Richard, Marcia E.,Ciccarelli, Rosa M.,Garcia, Kevin J.,Miller, Erica J.,Casino, Stephanie L.,Pike, Robert. D.,Stockland Jr, Robert A.
, p. 2167 - 2170 (2018)
Highly efficient transmetalation between gold phosphites and iodopalladium species is presented. In addition to successful transfer of cyclic and acyclic phosphites, studies involving P-chiral substrates revealed that an initial protodeauration as well as the target transmetalation were both stereospecific, and that the overall process occurred with retention of configuration at phosphorus. Building on the mechanistic work, a catalytic approach to the synthesis of chiral P-arylated nucleoside derivatives was developed. This chemistry has the potential to be easily adapted for the preparation of a diverse group of P-chiral species.
Vinyl- and dienylpalladium complexes formed via insertion of alkyne into sterically hindered Pd-aryl bonds
Yagyu,Osakada
, p. 1435 - 1436 (2007/10/03)
[PdI(C6H3Me2-2,6)(bpy)] reacts with excess amounts of dimethyl acetylenedicarboxylate to produce [PdI{CZ=CZ-(C6H3Me2-2,6)}(bpy)] (2, Z = COOMe) and [PdI{CZ=CZ-CZ=CZ(C6H3Me2-2,6)}(bpy)] (3). Crystallographic study revealed the molecular structures of 2 and 3 the latter of which has an s-trans dienyl ligand.
