37342-97-5 Usage
Reaction
Reagent for the hydrozirconation of olefins.
Reagent for the hydrozirconation of alkynes.
Catalyst for the hydroboration of olefins.
Mediates the reduction of tertiary amides to aldehydes, without reduction of cyano, nitro, ester, or α,β-unsaturated groups.
Catalyst for the asymmetric vinylation and dienylation of ketones.
Useful reagent for dimethylzinc mediated additions alkenylzirconocenes to aldimines.
Useful reagent for the synthesis of oxidized amides from nitriles.
Reagent for the hydrozirconation of propargylic alcohols.
Chemical Properties
white to beige powder
Uses
Different sources of media describe the Uses of 37342-97-5 differently. You can refer to the following data:
1. Functionalization of unsaturated systems via an organozirconium intermediate.
2. Bis(cyclopentadienyl)zirconium hydridochloride is used in the conversion of amides to aldehydes. It is also used as a pharmaceutical intermediate.
Purification Methods
It is moisture and light sensitive. Determine its purity by reaction with a slight excess of Me2CO whereby the active H reacts to produce Cp2ZrClOPri and the integrals of the residual Me2CO in the 1H NMR will show its purity. The presence of Cp2ZrH2 can be determined because it forms Cp2Zr(OPri)2. For a very active compound, it is best to prepare it freshly from the dichloride (see below) by reduction with Vitride [LiAl(OCH2CH2OH)2H2], the white precipitate is filtered off, washed with tetrahydrofuran, then Et2O and dried in a vacuum. Store it dry in the dark. [Carr & Schwartz J Am Chem Soc 101 3521 1979, Negishi & Takahashi Synthesis 1 1988, Beilstein 16 IV 1770.]
Check Digit Verification of cas no
The CAS Registry Mumber 37342-97-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,3,4 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 37342-97:
(7*3)+(6*7)+(5*3)+(4*4)+(3*2)+(2*9)+(1*7)=125
125 % 10 = 5
So 37342-97-5 is a valid CAS Registry Number.
InChI:InChI=1/2C5H.ClH.Zr.H/c2*1-2-4-5-3-1;;;/h2*1H;1H;;/q2*-5;;+1;/p-1/r2C5H.ClHZr/c2*1-2-4-5-3-1;1-2/h2*1H;2H/q2*-5;