373595-61-0Relevant articles and documents
Synthesis and QSAR studies of 4-substituted phenyl-2,6-dimethyl-3, 5-bis-N-(substituted phenyl)carbamoyl-1,4-dihydropyridines as potential antitubercular agents
Desai, Bhavik,Sureja, Dinesh,Naliapara, Yogesh,Shah, Anamik,Saxena, Anil K.
, p. 1993 - 1998 (2001)
Synthesis and QSAR studies of the title compounds have resulted in the identification of structural and physicochemical parameters (MR, σo, σm, σp) contributing to antitubercular activity. Among these, carbamoyl phenyl rin
Synthesis and pharmacological screening of some 1,4-dihydropyridine and their derivatives for anticonvulsant activity
Pattan, Shashikant R.,Purohit,Rasai,Mallya,Marihal,Khade,Paschapur
, p. 626 - 629 (2008/09/20)
A new series of 1,4-dihydropyridine and their derivatives have been synthesized and the structures of the compounds have been confirmed by IR and NMR. The title compounds are evaluated for anticonvulsant activity by maximal electroshock method. Some of these compounds have been found to exhibit excellent anticonvulsant activity.
Synthesis and evaluation of some 1, 4-dihydropyridine and their derivatives as antihypertensive agents
Pattan, Shashikant R.,Rasai,Venkatramana,Khade,Butle,Jadhav,Desai,Manvi
, p. 698 - 701 (2008/09/18)
A series of 1, 4-dihydro-2, 6-dimethyI-4-{4-[3-(2-aminopyrazine/l-amino-4- methyl piperazine)-2-hydroxy propoxy]phenyl}-pyridine-3, 5-carbamoyl have been synthesized and the structure of the compounds have been confirmed by IR, 1H NMR, MS & elemental analysis. The title compounds have been evaluated for antihypertensive activity by tail-cuff method. Some of these compounds have been found to exhibit excellent antihypertensive activity.
