37389-40-5Relevant articles and documents
Synthesis and study of prototropic tautomerism of 2-(2-hydroxyphenyl)-1-hydroxyimidazoles
Nikitina, Polina A.,Peregudov, Aleksandr S.,Koldaeva, Tatiana Yu.,Kuz'Mina, Ludmila G.,Adiulin, Evgeniy I.,Tkach, Iosif I.,Perevalov, Valery P.
, p. 5217 - 5228 (2015)
Novel 2-(2-hydroxyphenyl) substituted imidazoles have been synthesized. A prototropic tautomerism of the 1-hydroxyimidazole derivatives has been studied. X-ray diffraction analysis and IR-spectroscopy have revealed that in the solid state the title compounds exist as the N-hydroxy tautomers. The 1H and 13C NMR spectra of the new imidazole derivatives are discussed. It has been shown that in chloroform solutions 5-carbonyl substituted 2-(2-hydroxyphenyl)-1-hydroxyimidazoles exist in the N-hydroxy tautomeric form. A transition to DMSO results in the existence of the 1-hydroxyimidazoles under study as the N-oxide tautomers.
