3740-94-1

Upstream product

• 1469-94-9 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione 
• 4010-33-7 2-acetylphenyl benzoate 

Downstream Products

• 83548-87-2 4-bromo-3-(2-hydroxyphenyl)-1,5-diphenylpyrazole 

Relevant academic research and scientific papers

An efficient synthesis of 3-bromoflavones under solvent free conditions using grinding technique

Selective bromination of 1-(2-hydroxyphenyl)-3-phenylpropane- 1,3-diones has been carried out with ammonium bromide and ammonium persulphate at room temperature using grinding technique under solvent free conditions to give 2-bromo derivatives which on cyclodehydration with p-toluenesulphonic acid under grinding conditions give 3-bromoflavones. Also, flavones on bromination using above mentioned conditions give 3-bromoflavones directly.

Selective halogenation of 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones using phase transfer catalysis and synthesis of 3-chloro- and 3-bromo-flavones

Selective chlorination and bromination of 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones have been achieved by their reaction with ammonium chloride/ammonium bromide and hydrogen peroxide in biphase medium using phase transfer catalysis.