374116-14-0Relevant academic research and scientific papers
Design criteria for minimalist mimics of protein-protein interface segments
Taechalertpaisarn, Jaru,Lyu, Rui-Liang,Arancillo, Maritess,Lin, Chen-Ming,Jiang, Zhengyang,Perez, Lisa M.,Ioerger, Thomas R.,Burgess, Kevin
supporting information, p. 908 - 915 (2019/01/30)
Small molecules that can interrupt or inhibit protein-protein interactions (PPIs) are valuable as probes in chemical biology and medicinal chemistry, but they are also notoriously difficult to develop. Design of non-peptidic small molecules that mimic ami
Application of an automated synthesis suite to parallel solution-phase peptide synthesis
Kuroda,Hattori,Fujioka,Cork,Kitada,Sugawara
, p. 1147 - 1154 (2007/10/03)
An in-house developed automated synthesis suite was used to prepare a library of 72 tetrapeptide derivatives, the starting materials for pharmaceutically attractive pentapeptides, employing a convergent strategy. An initial set of 18 dipeptides were synth
