374633-29-1

Basic information

• Product Name: 4-BROMO-6-CYANOINDOLE
• Synonyms: 4-BROMO-6-CYANOINDOLE;4-bromo-1H-indole-6-carbonitrile;1H-Indole-6-carbonitrile, 4-broMo-
• CAS NO: 374633-29-1
• Molecular Formula: C₉H₅BrN₂
• Molecular Weight: 221.05
• EINECS: 200-258-5
• Mol File: 374633-29-1.mol

Chemical Properties

• Boiling Point: 379.8 °C at 760 mmHg
• Flash Point: 183.5 °C
• Appearance: /
• Density: 1.74
• Vapor Pressure: 5.7E-06mmHg at 25°C
• Refractive Index: 1.726
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 14.24±0.30(Predicted)
• CAS DataBase Reference: 4-BROMO-6-CYANOINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-6-CYANOINDOLE(374633-29-1)
• EPA Substance Registry System: 4-BROMO-6-CYANOINDOLE(374633-29-1)

Safety Data

• Hazardous Substances Data: 374633-29-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4-Bromo-6-cyanoindole is used as a key building block for the synthesis of indole-based compounds, which are essential in the development of pharmaceuticals. Its unique structure allows for the creation of a wide range of therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 4-Bromo-6-cyanoindole is used as a precursor in the synthesis of various agrochemicals, contributing to the development of effective pest control solutions and crop protection products.
Used in Research and Development:
4-Bromo-6-cyanoindole is utilized in research and development for new drug discovery, particularly in the area of anti-cancer agents. Its potential in this field is being explored through various scientific studies and experiments.
Used in Organic Synthesis:
4-BROMO-6-CYANOINDOLE is also used in organic synthesis for the production of a variety of organic compounds, which find applications in different industries, including the pharmaceutical sector.
Used in Cancer Treatment:
4-Bromo-6-cyanoindole is used as a potential anti-cancer agent, with ongoing research aimed at understanding its mechanism of action and effectiveness in treating various types of cancer. Its role in this application is significant due to the ongoing demand for new and effective cancer treatments.

InChI:InChI=1/C9H5BrN2/c10-8-3-6(5-11)4-9-7(8)1-2-12-9/h1-4,12H

Upstream product

• 885520-48-9 4-bromo-6-methyl-1H-indole 
• 6968-24-7 2,6-Dibromo-4-methylaniline 
• 1391575-90-8 2-(2,6-dibromo-4-methylphenyl)acetaldehyde 

Downstream Products

• 3613-02-3 4-methyl-1H-indole-6-carbonitrile 
• 1181566-91-5 1-{3-fluoro-4-[(phenylmethyl)oxy]phenyl}-4-hydroxy-1H-indole-6-carbonitrile 
• 1181566-61-9 1-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-1H-indole-6-carbonitrile 
• 955978-86-6 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole-6-carboxylic acid amide 
• 955979-23-4 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carbonitrile 
• 1310556-86-5 4-bromo-1-[(4-nitrophenyl)sulfonyl]-1H-indole-6-carbonitrile 
• 1181566-90-4 4-bromo-1-{3-fluoro-4-[(phenylmethyl)oxy]phenyl}-1H-indole-6-carbonitrile 

Relevant articles and documents

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Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.