Cas 374680-85-0,(S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester

374680-85-0

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Basic information

Product Name: (S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester
Synonyms: (S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester
CAS NO:374680-85-0
Molecular Formula:
Molecular Weight: 358.626
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester(CAS DataBase Reference)
NIST Chemistry Reference: (S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester(374680-85-0)
EPA Substance Registry System: (S)-2-[(R)-2-(tert-Butyl-dimethyl-silanyloxy)-1-hydroxy-ethyl]-5-trimethylsilanyl-pent-4-ynoic acid methyl ester(374680-85-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 374680-85-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 374680-85-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,4,6,8 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 374680-85:
(8*3)+(7*7)+(6*4)+(5*6)+(4*8)+(3*0)+(2*8)+(1*5)=180
180 % 10 = 0
So 374680-85-0 is a valid CAS Registry Number.

374680-85-0Upstream product

70681-41-3 (R)-dimethyl malate

374680-85-0Downstream Products

374680-85-0Relevant academic research and scientific papers

A convergent synthesis of the 11-oxa prostaglandin analogue AL-12182

Fox, Martin E.,Jackson, Mark,Lennon, Ian C.,McCague, Raymond

, p. 1227 - 1236 (2007/10/03)

(Chemical Equation Presented) The 11-oxa prostaglandin analogue AL-12182 1 has potent topical ocular hypotensive activity. A convergent and concise general synthesis of this class of prostanoid was developed employing a stereoselective coupling reaction between a tetrahydrofuran core electrophile and a nucleophilic omega side chain component, providing a route that should be suitable for commercial scale production. The tetrahydrofuran core was assembled from dimethyl D-malate using a stereoselective β-hydroxy ester dianion alkylation reaction.

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