374794-89-5

Basic information

• Product Name: 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate
• Synonyms: 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate;tert-butyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate;1-Oxa-8-azaspiro[4.5]decane-8-carboxylicacid
• CAS NO: 374794-89-5
• Molecular Formula: C₁₃H₂₃NO₃
• Molecular Weight: 241.33
• Product Categories: API intermediates
• Mol File: 374794-89-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 333.508°C at 760 mmHg
• Flash Point: 155.501°C
• Appearance: /
• Density: 1.08
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate(374794-89-5)
• EPA Substance Registry System: 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate(374794-89-5)

Safety Data

• Hazardous Substances Data: 374794-89-5(Hazardous Substances Data)

Usage

General Description

1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate, also known as Tert-butyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate, is a chemical compound that belongs to the class of spiro compounds. It is commonly used in pharmaceutical research and drug development due to its potential pharmacological properties. 1,1-Dimethylethyl 1-oxa-8-azaspiro[4.5]decane-8-carboxylate is of interest for its potential biological activity and therapeutic applications, particularly in the field of central nervous system disorders. The unique spiro structure of this compound makes it a valuable candidate for the development of new pharmaceuticals with diverse biological activities. Further research and studies are being conducted to explore its potential applications in the medical and pharmaceutical industry.

InChI:InChI=1/C13H23NO3/c1-12(2,3)17-11(15)14-8-6-13(7-9-14)5-4-10-16-13/h4-10H2,1-3H3

Upstream product

• 1192122-44-3 tert-butyl 4-[3-[[tert-butyl(dimethyl)silyl]oxy]propyl]-4-hydroxypiperidine-1-carboxylate 
• 301226-27-7 tert-butyl 2-oxo-1-oxa-8-azaspiro[4.5]decane-8-carboxylate 
• 374794-88-4 tert-butyl 4-hydroxy-4-(3-hydroxypropyl)piperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 374794-91-9 1,1-dimethylethyl 4-(3-ethoxy-3-oxoprop-1-yl)-4-hydroxy-1-piperidinecarboxylate 
• 374794-90-8 1,1-dimethylethyl 4-(3-ethoxy-3-oxo-1-propynyl)-4-hydroxy-1-piperidinecarboxylate 
• 1192122-45-4 tert-butyl 4-hydroxy-4-[3-[(methylsulfonyl)oxy]propyi]piperidine-1-carboxylate 

Downstream Products

• 3970-79-4 1-oxa-8-aza-sprio[4,5]decane hydrochloride 
• 176-92-1 4-dioxa-8-azaspiro[4.5]decane 

Relevant articles and documents

SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS

This invention relates to a new sordarin derivative or a pharmaceutically acceptable salt thereof, which has antimicrobial activities (especially, antifungal activities), to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases in a human being or an animal.

Cyclohexane derivatives and their use as therapeutic agents

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.