374812-80-3

Upstream product

• 374812-79-0 tert-Butyl 8-[3-[4-(4-chlorophenyl)-1-piperidinyl] propoxy]-1,3,4,5-tetrahydro-2H-2-benzazepine-2-carboxylate 

Downstream Products

• 374812-82-5 2-Acetyl-8-[3-[4-(4-chlorophenyl)-1-piperidinyl]propoxy]-2,3,4,5-tetrahydro-1H-2-benzazepine Hydrochloride 
• 374812-81-4 8-[3-[4-(4-Chlorophenyl)-1-piperidinyl]propoxy]-2-methyl-2,3,4,5-tetrahydro-1H-2-benzazepine Hydrochloride 

Relevant academic research and scientific papers

Melanin-concentrating hormone antagonist

A melanin-concentrating hormone antagonist comprising a compound of the formula: wherein R is hydrogen atom or a cyclic group which may be substituted; X is a bond or a spacer having a main chain of 1 to 10 atoms; Y is a spacer having a main chain of 1 to 6 atoms; ring A is benzene ring which may be further substituted; ring B is a 5- to 9-membered nitrogen-containing non-aromatic heterocyclic ring which may be further substituted; R1 and R2 are the same or different and are hydrogen atom, a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; or R1 and R2, together with the adjacent nitrogen atom, may form a nitrogen-containing heterocyclic ring which may be substituted; or R2, together with the adjacent nitrogen atom and Y, may form a nitrogen-containing heterocyclic ring which may be substituted; or a salt thereof is useful as a preventive or therapeutic agent for obesity, etc.